This book is quite frankly, mind-boggling. There is so much political maneuvering and so many factions at play it becomes hard to keep track of everything. 
The interesting thing about this book is that there is no clear black and white. The characters feel cold and grey which I feel that suits the tone of the book but could be a problem for some. There are many themes covered such as the environment, power and the effect of prediction. 
The main thing I liked about this book  is just the general plot. Seeing the journey of the main characters and seeing the intricacies of being pre-born and prescient was very intriguing. However, this book is not without its flaws. I mentioned at the start of this review that this book is mind-boggling and sometimes it just becomes too much to handle. The long philosophical passages just become too much at some point and it starts to drag. I feel like the book could have been a bit shorter.
Also, some characters feel vastly different from Dune: Messiah and maybe it's because of the nine-year gap in between the books but it feels a little off-putting.
In the end, while this book has its flaws, I did like it quite a bit and would recommend you to read it.

Edit: After some time contemplating, I've decided to lower my rating to 3.75 stars from 4 stars. I feel like the problems I mentioned impacted my experience more than I originally thought.